BDBM50161748 CHEMBL194085::[3-((R)-4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-acetic acid

SMILES OC(=O)Cn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=NONWUVBJQKYHHO-CQSZACIVSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50161748   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataKi:  0.510nMAssay Description:Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataKi:  540nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161748(CHEMBL194085 | [3-((R)-4-Fluoro-benzenesulfonylami...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of U-46,619-induced inositol phosphate accumulation at human Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed