BDBM50161925 CHEMBL3793159

SMILES CCN(CC)c1ccc(-c2ccccc2)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12

InChI Key InChIKey=AHRLZFQOAGYJQQ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161925   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50161925(CHEMBL3793159)
Show SMILES CCN(CC)c1ccc(-c2ccccc2)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12
Show InChI InChI=1S/C26H29ClN4O/c1-6-31(7-2)21-14-13-20(18-11-9-8-10-12-18)24-25(21)30(4)26(29-24)28-23-17(3)15-19(27)16-22(23)32-5/h8-16H,6-7H2,1-5H3,(H,28,29)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair