BDBM50164794 CHEMBL3798846::US11174250, Example Table4.1.1::US11319299, Comp. No. 57

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1

InChI Key InChIKey=DJOVLOYCGXNVPI-UHFFFAOYSA-N

Data  2 IC50  6 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164794   

TargetP61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534](Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM50164794(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Affinity DataIC50:  9.50E+3nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM50164794(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Affinity DataKd:  36nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair