BDBM50164848 CHEMBL3798179
SMILES CN(CCCCNC(=O)c1cc2ccccc2[nH]1)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23
InChI Key InChIKey=XRUUSJMEKAKGQU-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50164848
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 337nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 4.23E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at dopamine D2 receptor (unknown origin) by cAMP accumulation assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 155nMAssay Description:Agonist activity at renilla luciferase-tagged human dopamine D2 receptor expressed in HEK293 cells coexpressing mVenus-fused beta-arrestin 2 assessed...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 125nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells coexpressing renilla luciferase-fused Galphai1/GFP10-fused Ggamma2 by BRET a...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 154nMAssay Description:Agonist activity at dopamine D2 receptor (unknown origin) assessed as increase in beta-arrestin-2 recruitmentMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 23nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells coexpressing renilla luciferase-fused GalphaoA/GFP10-fused Ggamma2 by BRET a...More data for this Ligand-Target Pair