BDBM50165948 6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzyloxycarbonylamino-pentanoylamino}-hexanoic acid::CHEMBL192729

SMILES OC(=O)CCCCCNC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2o1

InChI Key InChIKey=MFTMRQDQKJTSPG-QFIPXVFZSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50165948   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of rat prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50165948(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed