BDBM50166213 17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one

SMILES CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@]3(CCC4=O)OCC=C)ccc5O

InChI Key InChIKey=YTYSMQUWSIEJSV-VCPZZJCDSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50166213   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  0.610nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  33.8nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataIC50:  63nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataIC50:  17.6nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed