BDBM501718 1-(3-((5-(3-(Dimethylamino)propoxy)-7-methyl-9-oxo-9H-xanthen-3-yl)oxy)phenyl)-3-phenylurea::US11028064, Example 32

SMILES CN(C)CCCOc1cc(C)cc2c1oc1cc(Oc3cccc(NC(=O)Nc4ccccc4)c3)ccc1c2=O

InChI Key InChIKey=JUOWDPFSSPMSSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501718   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501718(1-(3-((5-(3-(Dimethylamino)propoxy)-7-methyl-9-oxo...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501718(1-(3-((5-(3-(Dimethylamino)propoxy)-7-methyl-9-oxo...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent