BDBM501731 N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5-methyl-9-oxo-9H-xanthen-3-yl)oxy)pyridin-2-yl)propanamide::US11028064, Example 45

SMILES CN(C)CCOc1cc(C)c2oc3cc(Oc4ccc(CCC(=O)NC5CCCC5)nc4)ccc3c(=O)c2c1

InChI Key InChIKey=DQTLPPVIRNPWKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501731   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501731(N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5...)
Affinity DataIC50:  5.50E+3nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501731(N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent