BDBM501740 4-(2-(Dimethylamino)ethoxy)-2-methyl-6-((6-(3-(4-methylpiperazin-1-yl)-3-oxopropyl)pyridin-3-yl)oxy)-9H-xanthen-9-one::US11028064, Example 54

SMILES CN(C)CCOc1cc(C)cc2c1oc1cc(Oc3ccc(CCC(=O)N4CCC(N)CC4)nc3)ccc1c2=O

InChI Key InChIKey=MXDZVEADVUTJOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501740   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501740(4-(2-(Dimethylamino)ethoxy)-2-methyl-6-((6-(3-(4-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501740(4-(2-(Dimethylamino)ethoxy)-2-methyl-6-((6-(3-(4-m...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent