BDBM501750 N-Cyclopentyl-3-(5-((5-(3-((2R,6S)-2,6-dimethylpiperidin-1-yl)propoxy)-7-methyl-9-oxo-9H-xanthen-3-yl)oxy)pyridin-2-yl)propanamide::US11028064, Example 64

SMILES C[C@H]1CCC[C@@H](C)N1CCCOc1cc(C)cc2c1oc1cc(Oc3ccc(CCC(=O)NC4CCCC4)nc3)ccc1c2=O

InChI Key InChIKey=ZIAJHUUCWOCRBB-WMPKNSHKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501750   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501750(N-Cyclopentyl-3-(5-((5-(3-((2R,6S)-2,6-dimethylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501750(N-Cyclopentyl-3-(5-((5-(3-((2R,6S)-2,6-dimethylpip...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent