BDBM50175961 8-((trans, rac)-2-hydroxy-2-phenyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL200371
SMILES O[C@]1(CCCC[C@@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1
InChI Key InChIKey=BONFVDJOYDFOEN-WIOPSUGQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50175961
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 56nMAssay Description:Displacement of [3H]glycine from human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 2.60E+4nMAssay Description:Displacement of [3H]glycine from human GlyT2 by radiometric assayMore data for this Ligand-Target Pair