BDBM50176259 (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol::CHEMBL201531::TRAMADOL

SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C

InChI Key InChIKey=TVYLLZQTGLZFBW-UHFFFAOYSA-N

Data  8 KI  17 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176259   

TargetMu-type opioid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataKi:  2.00E+3nMAssay Description:Opioid receptor mu 1 agonist activity with monoamine (NE, 5-HT) uptake-blocking activity in the 0.8-1 uM rangeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed