BDBM50176259 (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol::CHEMBL201531::TRAMADOL

SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C

InChI Key InChIKey=TVYLLZQTGLZFBW-UHFFFAOYSA-N

Data  8 KI  17 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50176259   

TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 790nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of reuptake of 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed