BDBM50176259 (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol::CHEMBL201531::TRAMADOL

SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C

InChI Key InChIKey=TVYLLZQTGLZFBW-UHFFFAOYSA-N

Data  8 KI  17 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176259   

TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataKi:  14nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176259BDBM50176259(TRAMADOL | (1R,2R)-2-[(dimethylamino)methyl]-1-(3-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human KOR expressed in CHO cell membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details Article
PubMed