BDBM50177293 CHEMBL202095::N-(4-methyl-2-(4-methyl-1,4-diazepan-1-yl)quinolin-6-yl)-2-(4-(trifluoromethoxy)phenoxy)acetamide

SMILES CN1CCCN(CC1)c1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1

InChI Key InChIKey=XCJZSOSDRGLOMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177293   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177293(CHEMBL202095 | N-(4-methyl-2-(4-methyl-1,4-diazepa...)
Affinity DataIC50:  244nMAssay Description:Displacement of [3H]myo-inositol from human MCH1 receptor expressed in CHO cell by IP3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177293(CHEMBL202095 | N-(4-methyl-2-(4-methyl-1,4-diazepa...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human MCH1 receptor by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177293(CHEMBL202095 | N-(4-methyl-2-(4-methyl-1,4-diazepa...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in CHO cell by WC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed