BDBM50177593 (5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-[2-chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-methanone::(5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)(2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl)methanone::CHEMBL363910::VNA-932::WAY-VNA-932

SMILES Cc1ccn(n1)-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1

InChI Key InChIKey=JXKQHDZUZGKDGO-UHFFFAOYSA-N

Data  10 KI  7 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50177593   

TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataKi:  125nMAssay Description:Binding affinity to OTR receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataKi:  199nMAssay Description:Displacement of [3H]-AVP from human OXR receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataKi:  199nMAssay Description:Displacement of [3H]AVP from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetOxytocin receptor(Rat)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  55nMAssay Description:Antagonist activity at OXR receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataEC50:  125nMAssay Description:Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assayMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetOxytocin receptor(Human)
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  353nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed