BDBM50178263 CHEMBL3814350

SMILES CCCc1cc(nc(N)n1)-c1c[nH]c2ncccc12

InChI Key InChIKey=LZXOEEWQLBVYGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178263   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178263(CHEMBL3814350)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human His6-tagged PDK1 using biotinylated PDKtide as substrate after 60 mins by topcount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178263(CHEMBL3814350)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1 in human PC3 cells assessed as reduction in AKT Thr308 phosphorylation after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed