BDBM50178289 CHEMBL3814343

SMILES CCc1cc(nc(N)n1)-c1c[nH]c2ncc(cc12)-c1c(C)nn(C)c1C

InChI Key InChIKey=YYBPZWIFCIMNCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178289   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178289(CHEMBL3814343)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human His6-tagged PDK1 using biotinylated PDKtide as substrate after 60 mins by topcount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178289(CHEMBL3814343)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1 in human PC3 cells assessed as reduction in AKT Thr308 phosphorylation after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed