BDBM50179929 2'-Fluoro-5'-[8-fluoro-7-(1-hydroxy-1-methyl-ethyl)-imidazo[1,2-a]pyridin-3-yl]-biphenyl-2-carbonitrile::CHEMBL202952

SMILES CC(C)(O)c1ccn2c(cnc2c1F)-c1ccc(F)c(c1)-c1ccccc1C#N

InChI Key InChIKey=FIXFKUDATBTRAZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179929   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179929(2'-Fluoro-5'-[8-fluoro-7-(1-hydroxy-1-methyl-ethyl...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Ro 15-1788 from human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cellsMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179929(2'-Fluoro-5'-[8-fluoro-7-(1-hydroxy-1-methyl-ethyl...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]Ro 15-1788 from human GABA-Aalpha3 receptor plus beta3gamma2 expressed in mouse L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed