BDBM50182305 7-((3-fluoro-5-(1-hydroxy-1-(thiazol-2-yl)propyl)phenoxy)methyl)-4-(4-fluorophenyl)-2H-chromen-2-one::CHEMBL205222
SMILES CCC(O)(c1nccs1)c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccc(F)cc2)c1
InChI Key InChIKey=RVORRAPNNOTJLM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50182305
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of human 5-LOMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of LTB4 production in calcium ionophore A23187-stimulated human whole bloodMore data for this Ligand-Target Pair