BDBM50182801 (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8::(3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol::5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE::AFEGOSTAT TARTRATE::CHEMBL206468::D-Isofagomine::US10081601, Example 1.1::US9796680, Example Table2.1::isofagomine

SMILES OC[C@H]1CNC[C@@H](O)[C@@H]1O

InChI Key InChIKey=QPYJXFZUIJOGNX-HSUXUTPPSA-N

Data  6 KI  20 IC50

PDB links: 26 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182801   

TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
The National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of non-phosphorylated form of rabbit muscle glycogen phosphorylase in presence of phosphateMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
The National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of non-phosphorylated form of rabbit muscle glycogen phosphorylaseMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
The National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  670nMAssay Description:Inhibition of phosphorylated form of pig liver glycogen phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
The National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  760nMAssay Description:Inhibition of phosphorylated form of rabbit muscle glycogen phosphorylaseMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Rattus norvegicus)
The National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  680nMAssay Description:Inhibition of phosphorylated form of rat liver glycogen phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed