BDBM50182801 (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8::(3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol::5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE::AFEGOSTAT TARTRATE::CHEMBL206468::D-Isofagomine::US10081601, Example 1.1::US9796680, Example Table2.1::isofagomine

SMILES OC[C@H]1CNC[C@@H](O)[C@@H]1O

InChI Key InChIKey=QPYJXFZUIJOGNX-HSUXUTPPSA-N

Data  6 KI  20 IC50

PDB links: 26 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182801   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  59nMAssay Description:Inhibition of GCase assessed as 4-methylumbelliferone release assay after 30 mins by fluorimetryMore data for this Ligand-Target Pair