BDBM50183783 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-(4-methoxyphenyl)-3-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)succinamide::CHEMBL208181

SMILES CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C

InChI Key InChIKey=MWYSQPGMUZLIHV-RCCFBDPRSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50183783   

TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183783((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183783((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataKi:  3nMAssay Description:Binding affinity to recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183783((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataKi:  12nMAssay Description:Binding affinity to recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183783((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataKi:  57nMAssay Description:Binding affinity to recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50183783((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataIC50:  484nMAssay Description:Inhibition of LPS/interferon gamma-stimulated TNFalpha release from HPBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed