BDBM50184868 CHEMBL378489::N-Benzoyl-N'-{4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl}-thiourea

SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=ATWXIAXXSMESBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184868   

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184868(CHEMBL378489 | N-Benzoyl-N'-{4-[(6,7-dimethoxy-4-q...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184868(CHEMBL378489 | N-Benzoyl-N'-{4-[(6,7-dimethoxy-4-q...)
Affinity DataIC50:  938nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed