BDBM50185356 1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-carboxylic acid::1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carboxylic acid::CHEMBL205892

SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(O)=O)cc1

InChI Key InChIKey=QGRRJJFZKZREIR-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50185356   

TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human isolated cPLA2alpha by vescicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  410nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of FAAH from rat brain microsomes by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of cPLA2 in human platelets assessed as arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed