BDBM50185453 3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(1-methyl-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL379365

SMILES Cn1nc(CC(CC(O)=O)c2cnc(s2)-c2ccc(Cl)cc2)cc1OCCc1ccc2CCCNc2n1

InChI Key InChIKey=XKXMEMPIHRKAQX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185453   

TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185453(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(1-methyl-5-(...)
Affinity DataIC50: 189nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed