BDBM50185699 CHEMBL3824337

SMILES Cn1nc(C(O)=O)c2ccc(cc12)C1CC1c1ccc(OCc2c(noc2C2CC2)-c2c(Cl)cccc2Cl)cc1Cl

InChI Key InChIKey=XVRQMMDRSOAMJJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185699   

TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185699(CHEMBL3824337)
Affinity DataEC50:  14nMAssay Description:Agonist activity at C-terminal Gal4-tagged human FXR (187 to 472 residues) expressed in HEK-293 cells co-expressing pFRluc by mammalian one hybrid as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185699(CHEMBL3824337)
Affinity DataEC50:  13nMAssay Description:Agonist activity at C-terminal Gal4-tagged human FXR (187 to 472 residues) expressed in HEK-293 cells co-expressing pFRluc by mammalian one hybrid as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed