BDBM50186527 (R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-phenylcyclobutanamine::CHEMBL212428

SMILES C[C@@H](OCC1(CC(N)C1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=NQQVDBGEUDENFZ-XYJCDUHRSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186527   

TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186527((R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)m...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186527((R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)m...)
Affinity DataKi:  4.05E+3nMAssay Description:Displacement of [3H]neurokinin B from human recombinant NK3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed