BDBM50187192 7-(4-fluorobenzyl)-9-hydroxy-6-methylene-8-oxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl dimethylsulfamate::CHEMBL377621

SMILES CN(C)S(=O)(=O)Oc1c2C(=C)N(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12

InChI Key InChIKey=VTUOOQGXKLBRMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187192   

TargetIntegrase(Human immunodeficiency virus 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50187192(7-(4-fluorobenzyl)-9-hydroxy-6-methylene-8-oxo-7,8...)
Affinity DataIC50:  420nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in MT4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed