BDBM50187225 (S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyrrolidine-2-carboxylic acid::1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE::CHEMBL210593

SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O

InChI Key InChIKey=OWYKAFABUYXQLE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187225   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187225((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187225((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of HCV helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187225((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187225((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187225((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of calf thymus polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed