BDBM50192284 CHEMBL3901211::US10239870, Example 15

SMILES Cc1ncoc1-c1nnc(SCCCN2CC[C@@]3(C[C@@H]3c3ccccc3)C2)n1C

InChI Key InChIKey=AAPXNHMQKBDDJN-XMSQKQJNSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192284   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Indivior

US Patent
LigandPNGBDBM50192284(CHEMBL3901211 | US10239870, Example 15)
Affinity DataKi:  28.2nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM50192284(CHEMBL3901211 | US10239870, Example 15)
Affinity DataKi:  4.17E+3nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
In DepthDetails US Patent