BDBM50192468 CHEMBL3923282
SMILES C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O
InChI Key InChIKey=LUDUMCCMFRYVOR-ZYELEKFWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50192468
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 338nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair