BDBM50192795 CHEMBL219081::N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)-2-(6-methylamino-pyridin-3-yl)-isobutyramide

SMILES CNc1ccc(cn1)C(C)(C)C(=O)N[C@H]1C2C[C@@H]3C[C@H]1C[C@](CC(N)=O)(C3)C2

InChI Key InChIKey=WRLITWGJOVVDNY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192795   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 310nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)...)
Affinity DataIC50: 246nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed