BDBM50196789 CHEMBL3892788

SMILES Cc1nnc(C)n1-c1ccc(O[C@@H]2[C@H](Cc3c2cc(Cl)cc3Cl)N2CC[C@@H](O)C2)c(F)c1

InChI Key InChIKey=XMPNZDWSSQEZEJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196789   

TargetSodium/hydrogen exchanger 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196789BDBM50196789(CHEMBL3892788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human NHE1 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed