BDBM50197300 CHEMBL3912164::ebselen derivative 2e

SMILES COc1ccccc1NC(=O)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1OC

InChI Key InChIKey=WNFPBFJRJMQTGX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197300   

TargetMicrotubule-associated protein 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50197300(CHEMBL3912164 | ebselen derivative 2e)
Affinity DataIC50:  6.79E+3nMAssay Description:Non-covalent/mixed type inhibition of recombinant human MetAP2 using Met-AMC as substrate preincubated for 30 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197300(CHEMBL3912164 | ebselen derivative 2e)
Affinity DataIC50:  263nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197300(CHEMBL3912164 | ebselen derivative 2e)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant SARS CoV-2 PL protease incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197300(CHEMBL3912164 | ebselen derivative 2e)
Affinity DataIC50:  263nMAssay Description:The inhibitor was screened against recombinant PL​pro​SARS and PL​pro​CoV2 at 37°Cin the assay buffer as described above. For...More data for this Ligand-Target Pair
In DepthDetails