BDBM50197692 CHEMBL3895337

SMILES Cc1nc2ccc(cc2[nH]1)-n1ncc(C(=O)c2cc3ccc(C)cc3[nH]2)c1N

InChI Key InChIKey=VXIMXYPRIKHTPC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50197692   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as reduction in channel currents at -80 mV holding potential by automated whole-cell patch cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  180nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  370nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  18nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50197692(CHEMBL3895337)
Affinity DataIC50:  340nMAssay Description:Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed