BDBM50197877 CHEMBL3892118

SMILES Oc1cccc2ccc(CN(CCC3CCN(Cc4ccccc4)CC3)CC#C)nc12

InChI Key InChIKey=ZAOLYIRFSLIUAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197877   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50:  3.56E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed