BDBM50197882 CHEMBL3959466

SMILES Cc1c(\C=C\c2ccc(Cl)o2)occ1C(O)=O

InChI Key InChIKey=YRBBUQXCLPLUDT-DUXPYHPUSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197882   

TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataIC50:  2.04E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataIC50:  2.02E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for first binding sit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataKd:  357nMAssay Description:Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for second binding si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed