BDBM50197883 CHEBI:78538::FX-1006::Tafamidis::US10377729, Compound Tafamidis::Vyndaqel

SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1


Data  9 IC50  14 Kd

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197883   

TargetTransthyretin(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair