BDBM50199952 CHEMBL219044::methyl 3-(((7R,8R,9alphaR)-8-(3-hydroxyphenyl)-7,8-dimethylhexahydro-1H-pyrido[1,2-R]pyrazin-2(6H)-yl)methyl)benzoate
SMILES COC(=O)c1cccc(CN2CCN3C[C@H](C)[C@@](C)(C[C@@H]3C2)c2cccc(O)c2)c1
InChI Key InChIKey=WIDFGVZFEPVCRU-QRJOEMBSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50199952
Affinity DataKi: 11nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Antagonist activity assessed as inhibition of U50488-stimulated [35S]GTP-gamma-S binding to human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity assessed as inhibition of loperamide-stimulated [35S]GTPgammaS binding to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair