BDBM50203426 CHEMBL3962413

SMILES CC[C@@H]1C[C@@](O)([C@@H](Nc2cccc3[nH]c(=O)ccc23)c2cc(F)c(F)c(O)c12)C(F)(F)F

InChI Key InChIKey=VZPLUSXTJULLCS-SYQZRHMFSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50203426   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50:  1.20nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding affinity to recombinant human androgen receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding affinity to recombinant human mineralocorticoid receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50:  63nMAssay Description:Transrepression activity at glucocorticoid receptorin human HeLa cells assessed as inhibition of TPA-induced collagenase promoter activity by lucifer...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50:  6.30nMAssay Description:Transrepression activity at glucocorticoid receptor in human THP1 cells assessed as receptor-mediated anti-inflammatory activity by measuring inhibit...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50:  10nMAssay Description:Binding affinity to recombinant human glucocorticoid receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50:  6.30nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50203426(CHEMBL3962413)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding affinity to recombinant human progesterone receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed