BDBM50206006 7,8-Dihydroxy-2H-1-benzopyran-2-one::7,8-dihydroxy-2H-chromen-2-one::7,8-dihydroxycoumarin::CHEMBL244948::Daphnetol

SMILES Oc1ccc2ccc(=O)oc2c1O

InChI Key InChIKey=ATEFPOUAMCWAQS-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206006   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  1.18E+4nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  7.67E+3nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  3.90E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydrox...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed