BDBM50208573 3-[1'-{4'-(Ethoxycarbonyl)-phenyl}]-quinuclidine-2-ene::CHEMBL259665::ethyl 4-(1-aza-bicyclo[2.2.2]oct-2-en-3-yl)benzoate

SMILES CCOC(=O)c1ccc(cc1)C1=CN2CCC1CC2

InChI Key InChIKey=NNXWGBRKIMLHHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208573   

TargetSqualene synthase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208573(3-[1'-{4'-(Ethoxycarbonyl)-phenyl}]-quinuclidine-2...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208573(3-[1'-{4'-(Ethoxycarbonyl)-phenyl}]-quinuclidine-2...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208573(3-[1'-{4'-(Ethoxycarbonyl)-phenyl}]-quinuclidine-2...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed