BDBM50212293 (1S,9R,10R)-5-amino-20-(cyclopropylmethyl)-6-thia-4,20-diazapentacyclo[8.7.3.0^{1,9}.0^{3,7}.0^{12,17}]icosa-3(7),4,12(17),13,15-pentaen-15-ol::CHEMBL226217
SMILES Nc1nc2C[C@]34CCN(CC5CC5)[C@H](Cc5ccc(O)cc35)[C@@H]4Cc2s1
InChI Key InChIKey=HBUZKCMRMAMMDZ-YRISNDGFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50212293
Affinity DataKi: 0.0700nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human mu opioid receptor transfected in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 0.340nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO membrane assessed as inhibition of U50488-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.610nMAssay Description:Agonist activity at human kappa opioid receptor transfected in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintilla...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair