BDBM50214105 3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridine::CHEMBL249096

SMILES COCc1cccc2nc([nH]c12)-c1[nH]nc2ncc(cc12)-c1ccncc1

InChI Key InChIKey=VCQAGQAPRXRROI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50214105   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214105(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214105(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214105(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214105(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed