BDBM50214113 CHEMBL251739::N,N-diethyl-2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide

SMILES CCN(CC)C(=O)c1cccc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cncc2ccccc12

InChI Key InChIKey=WALDVLHIHTVOPR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214113   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214113(CHEMBL251739 | N,N-diethyl-2-(5-(isoquinolin-4-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214113(CHEMBL251739 | N,N-diethyl-2-(5-(isoquinolin-4-yl)...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214113(CHEMBL251739 | N,N-diethyl-2-(5-(isoquinolin-4-yl)...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of RET kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214113(CHEMBL251739 | N,N-diethyl-2-(5-(isoquinolin-4-yl)...)
Affinity DataIC50:  53nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214113(CHEMBL251739 | N,N-diethyl-2-(5-(isoquinolin-4-yl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed