BDBM50214744 (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid::(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid (10)::CHEMBL32749::Ferulic acid (M5)::ferulic acid
SMILES COc1cc(\C=C\C(O)=O)ccc1O
InChI Key InChIKey=KSEBMYQBYZTDHS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 45 hits for monomerid = 50214744
Affinity DataIC50: 9.39E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of PKM2 (unknown origin)More data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of PKM2 (unknown origin)More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Human)
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo
Curated by ChEMBL
University of S£O Paulo
Curated by ChEMBL
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo
Curated by ChEMBL
University of S£O Paulo
Curated by ChEMBL
Affinity DataIC50: 4.13E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 min before substrate addition and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 integrase by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.44E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysisMore data for this Ligand-Target Pair
TargetSortase family protein(Staphylococcus aureus)
Indian Institute of Technology Delhi
Curated by ChEMBL
Indian Institute of Technology Delhi
Curated by ChEMBL
Affinity DataIC50: 1.32E+6nMAssay Description:Inhibition of Staphylococcus aureus SrtAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.86E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human serum BuChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human erythrocytes AChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using BTC as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Human)
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.26E+5nMAssay Description:Inhibition of human biotinylated amyloid beta (1 to 42) oligomerization assessed as decrease in oligomer abundance measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition of xanthine oxidase (XO) by each isolated phenolics was measured by following the decrease in the uric acid formation at 293nm at 25°...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+5nMAssay Description:The assay was performed using isolated phenolics from maize, and inhibition was determined according to previously described method.More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylcholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of mushroom tyrosinase after 25 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 15 mins before acetylthiocholine chloride substrate addition by Ellman assayMore data for this Ligand-Target Pair
Affinity DataKi: 360nM ΔG°: -8.78kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Binding affinity to CK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.89E+3nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze
Universit�� Degli Studi Di Firenze
Affinity DataKi: 3.50E+3nM ΔG°: -7.44kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 7.04E+3nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze
Universit�� Degli Studi Di Firenze
Affinity DataKi: 7.13E+3nM ΔG°: -7.02kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 7.41E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.45E+3nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.43E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.43E+3nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.78E+3nMAssay Description:Inhibition of human catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.78E+3nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.87E+3nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.08E+4nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+4nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+4nMAssay Description:Inhibition of mouse CA13 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+4nMAssay Description:Inhibition of mouse carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.08E+5nM ΔG°: -4.62kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+5nM ΔG°: -5.01kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair