BDBM50218261 CHEMBL74631

SMILES COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OCCCCCc1ccccc1

InChI Key InChIKey=TXOSLUBAGDRKHQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50218261   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218261(CHEMBL74631)
Affinity DataKi:  13nMAssay Description:Inhibition of rolipram binding to PDE4 from human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218261(CHEMBL74631)
Affinity DataIC50:  57nMAssay Description:Inhibition of Phosphodiesterase 4 from human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218261(CHEMBL74631)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against phosphodiesterase 4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218261(CHEMBL74631)
Affinity DataIC50:  57nMAssay Description:In vitro inhibitory concentration against phosphodiesterase 4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed