BDBM50222145 CHEMBL237060::methyl 2-(5-((S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-2H-tetrazol-2-yl)-2-phenylacetate

SMILES COC(=O)C(c1ccccc1)n1nnc(n1)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N

InChI Key InChIKey=GDALGIMYCYQPDB-MRTLOADZSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222145   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222145(CHEMBL237060 | methyl 2-(5-((S)-1-(2-amino-2-methy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]Ghrelin from human GHSR1a after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222145(CHEMBL237060 | methyl 2-(5-((S)-1-(2-amino-2-methy...)
Affinity DataEC50:  3.17E+3nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed