BDBM50223025 CHEMBL249212::N2-(3,5-dichloropyridin-2-yl)-3,6-diethyl-N5-((1R,2S)-2-(2-fluoroethoxy)-2,3-dihydro-1H-inden-1-yl)-N2-methylpyrazine-2,5-diamine

SMILES CCc1nc(N(C)c2ncc(Cl)cc2Cl)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCF

InChI Key InChIKey=AXRGGNRDBYIQOI-FCHUYYIVSA-N

Data  1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223025   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50223025(CHEMBL249212 | N2-(3,5-dichloropyridin-2-yl)-3,6-d...)
Show SMILES CCc1nc(N(C)c2ncc(Cl)cc2Cl)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCF
Show InChI InChI=1S/C25H28Cl2FN5O/c1-4-19-23(32-22-17-9-7-6-8-15(17)12-21(22)34-11-10-28)30-20(5-2)25(31-19)33(3)24-18(27)13-16(26)14-29-24/h6-9,13-14,21-22H,4-5,10-12H2,1-3H3,(H,30,32)/t21-,22+/m0/s1
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cellsMore data for this Ligand-Target Pair